Humulus: Hops effects on the nervous system

by Paul Bergner

Medical Herbalism 6(1):13

Summary: Hop (Cannabidaceae)(Cannabaceae) extracts were administered to mice of equal weights and age at doses of 100mg, 250mg, or 500mg/kg 30 minutes before each test. Standard animal tests showed a sedative effect on motor activity, increased anticonvulsant activity, analgesia, enhanced sleep-inducement, and, at the highest dose, a significant fall in rectal temperature.

Commentary: Hops (Humulus lupulus) (Cannabidaceae)(Cannabaceae) has a well known reputation as a nervine. This research has reiterated what is well known, and added information about temperature reduction. It is no surprise that a relative of Cannabis would be used to relax the central nervous system.

K.M. Lee J.S. Jung et al. “Effects of Humulus lupulus extract on the central nervous system in mice. Planta Medica 1993;59:A691
Copyright 2001 Paul Bergner   

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