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Humulus: Hops effects on the nervous system by Paul Bergner Medical Herbalism 6(1):13 Summary: Hop (Cannabidaceae)(Cannabaceae) extracts were administered to mice of equal weights and age at doses of 100mg, 250mg, or 500mg/kg 30 minutes before each test. Standard animal tests showed a sedative effect on motor activity, increased anticonvulsant activity, analgesia, enhanced sleep-inducement, and, at the highest dose, a significant fall in rectal temperature. Commentary: Hops (Humulus lupulus) (Cannabidaceae)(Cannabaceae) has a well known reputation as a nervine. This research has reiterated what is well known, and added information about temperature reduction. It is no surprise that a relative of Cannabis would be used to relax the central nervous system. K.M.
Lee J.S. Jung et al. “Effects of
Humulus lupulus extract on the central nervous
system in mice. Planta
Medica 1993;59:A691
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